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PTK2 protein tyrosine kinase 2 (PTK2), also known as focal adhesion kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. PTK2 is a focal adhesion -associated protein kinase involved in cellular adhesion (how cells stick to each other and their surroundings) and spreading processes (how cells move around) This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents PTK2 (FAK), a protein tyrosine kinase in the RTK pathway, is an important mediator within the cell migration process, as well as in cell proliferation and cell survival. Substantial evidence has shown that activated PTK2 leads to tumor growth and metastasis [129] , and the level of expression is substantially linked to the invasive potential of tumors [134] Gene target information for PTK2 - protein tyrosine kinase 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments PTK2 (FADK, FAK, FAK1, PPP1R71) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies

PTK2 inhibition-induced sustained levels of ATG3 were able to sensitize cancer cells to DNA-damaging agents. High FAK expression is associated with Ovarian Cancer. Generally, this study indicates that miR-3173 negatively regulates PTK2 and inhibits proliferation and invasion of B-ALL cell lines. Thus, miR-3173 may represent a potential therapeutic molecule for B-ALL intervention. elevated.

Looking for online definition of PtK2 or what PtK2 stands for? PtK2 is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms PtK2 is listed in the World's largest and most authoritative dictionary database of abbreviations and acronym PtK2 cells are resistant to adenovirus 5, coxsackievirus B5, and poliovirus 2. They are susceptible to coxsackievirus A9, herpes simplex, vaccinia, and vesicular stomatitis (Ogden strain). PtK 2 cells contain intermediate filaments composed of Keratin. Reference PTK2 proteinska tirozinska kinaza 2 (PTK2, Fokalna adheziona kinaza, FAK), protein je koji je kod ljudi kodiran PTK2 genom. PTK2 je fokalna proteinska kinaza koja učestvuje u ćelijskoj adheziji (vazivanje ćelija za njihovo okruženje) i procesu širenja ćelija (kretanju ćelija). Poznato je da kad je FAK blokiran, ćelija raka dojke postaju u manjoj meri metastatične usled umanjene.

PTK2 - Wikipedi

  1. An important paralog of this gene is PTK2. UniProtKB/Swiss-Prot Summary for PTK2B Gene. Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and.
  2. Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development
  3. PTK2; protein tyrosine kinase 2: Aliases: FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK : Location: 8q24.3: Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases.
  4. PTK2 - Explore an overview of PTK2, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data
  5. Ptk2 was activated by Pkce in neonatal rat ventricular myocytes. These data are indicative of an involvement of focal adhesion kinase-dependent signaling pathway in the evolution of hypoxia-ischemia induced neuronal degeneration; in endothelial cell barrier exposed to hyperosmolar challenge, the involvement of focal adhesion kinase was critical in establishing barrier strengthening ; Therefore.
  6. Cell atlas. Showing subcellular location of PTK2 (FADK, FAK, FAK1, PPP1R71)
  7. PTK2 / YJR059W Overview Standard Name PTK2 1 Systematic Name YJR059W SGD ID SGD:S000003820 Aliases STK2 5 Feature Type ORF , Verified Description Serine/threonine protein kinase; involved in regulation of ion transport across plasma.

PTK2 protein. Gene. PTK2. Organism. Homo sapiens (Human) Status. Unreviewed-Annotation score: -Experimental evidence at protein level i. Function i GO - Molecular function i. ATP binding Source: InterPro; protein tyrosine kinase. Search external sites for PTK2. PubMed (entries) GeneCards; GTEx; NCBI; View details . Choose a dataset. CRISPR (Avana) Public 20Q4. CRISPR (Avana) Public 20Q4; CRISPR (GeCKO) 19Q1; CRISPR (Sanger) Combined RNAi (Broad, Novartis, Marcotte) RNAi (Broad) RNAi (Novartis) Find cell lines: None . None; Create/edit a list ; Show lineage subtypes. CRISPR (Avana) Public 20Q4. Expression Public 20Q4. Bilder von PtK2 Zellen ptk2-pict.pdf × Schließen. Galerie als Vollbild anzeigen. Downloads Product information PtK-2 cells MSDS PtK-2 cells. Alternativen. PtK2 growing 410,00 € PtK2 gDNA 95,00 € PtK2 (NBL-5) cell pellet 125,00 € Any Questions? Please contact us at: +49 (0)6221 700799. info@clsgmbh.de. Kontaktieren Sie uns Gerne helfen wir Ihnen weiter. per Telefon +(49) 06221 700799. PTK2/FAK1, rather than by PTK2/FAK1 itself. Promotes phosphorylation of BCAR1; GIT2 and SHC1; this requires both SRC and PTK2/FAK1. Promotes phosphorylation of BMX and PIK3R1. Isoform 6 (FRNK) does not contain a kinase domain and inhibits PTK2/FAK1 phosphorylation and signaling. Its enhanced expression can attenuate the nuclea

PTK2 (FAK), FADK, FAK1: KinaseFamily: FAK Kinase Family: Protein Tag: GST Tag: Contents & storage. Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. Videos ; Brands. Shopping Tool. Product Selection Guides; Quick Order; Redeem a Quote. Go. PTK2 (PTK2 protein tyrosine kinase 2), Authors: Joerg Schwock, Neesha Dhani. Published in: Atlas Genet Cytogenet Oncol Haematol

PTK2 Gene - GeneCards FAK1 Protein FAK1 Antibod

Moreover, PTK2 expression was negatively correlated with its level of promoter methylation. PTK2 apparently acts as an oncogene by increasing CSC traits and tumorigenicity in HCC. The present data suggest that PTK2 may be a novel prognostic biomarker for HCC recurrence, and a therapeutic target for HCC treatment PTK2 appears to be a major substrate for the Rous virus-encoded oncoprotein, pp60v-src (see SRC, 190090), which transforms and confers anchorage independence on chicken embryo fibroblasts (Schaller et al., 1992). A marked increase in tyrosine phosphorylation of PTK2 is also observed after treatment of cells with cholecystokinin, bombesin, vasopressin, and endothelin. Thus, activation of PTK2. This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of.

Molecular Expressions Microscopy Primer: Specialized

PTK2 - an overview ScienceDirect Topic

  1. Proteomic analysis identified PTK2/FAK overexpression is a biomarker of radioresistance in locally advanced HNSCC, and PTK2/FAK inhibition radiosensitized HNSCC cells. Combinations of PTK2/FAK inhibition with radiotherapy merit further evaluation as a therapeutic strategy for improving local control
  2. Antibody information for antibodies HPA001842, HPA029671 and CAB004036 used in analysis of ENSG00000169398 / PTK2
  3. PtK2 (NBL-5) cell pellet. Artikelnummer: 608316CP. 125,00 € je Unit zzgl. MwSt. zzgl Versandkosten ×.
  4. CD61 bindet zudem PTK2, ITGB3BP, TLN1 und CIB1. Das Heterodimer aus Integrin α-V und β-3 ist der zelluläre Rezeptor für das Zytomegalievirus (HHV-5), HHV-8, das Coxsackievirus A9, das Hantavirus, das humane Metapneumovirus, das humane Parechovirus 1 und das West-Nil-Virus
  5. PtK2 cells were seeded sparsely on a coverslip and allowed to grow into microcolonies of about 25 cells. (A) Cells were stained with the membrane potential-sensitive dye DiOC 6. Shown is a single microcolony. The cross indicates the center, and the dotted line indicates the rim of the microcolony as used for the subsequent analysis. (Scale bar: 50 μm.) B) Plot of the average DiOC 6.
  6. Holiday Schedule: Addgene will be closed December 24 - January 1. Order processing and shipping will resume on January 4, 2021. For questions about estimated ship dates, please feel free to track your order status or contact [email protected]
Male Rat Kangaroo Kidney Epithelial Cells (PtK2 Line

PTK2 (human) Gene Target - PubChe

Anti-Focal adhesion kinase 1 (PTK2) (Hu,Ms,Rt) aus Kaninchen - unkonj. - Dianov PTK2 has been shown to play an important role in adhesion, spreading, motility, invasion, metastasis, survival, angiogenesis, epithelial to mesenchymal transition (EMT), cancer stem cells and the tumor microenvironment. 2, 3 Overexpression and activation of PTK2 is associated with several human malignant diseases, and is correlated with poor overall patient survival. 4-6 The focal adhesion. CD63 ist ein Oberflächenprotein aus der Gruppe der Tetraspanine.. CD63 dient in der Medizin als Marker für die Aktivierung von Basophilen (ein Typ der Immunzellen) und wird zur Diagnose einer Immunglobulin-E-basierten Allergie verwendet (basophil activation test, BAT). Weiterhin wird es in der Biochemie zur Lokalisierung bestimmter Membranstrukturen (den multivesicular bodies) innerhalb von.

PTK2 has 9,170 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 98 datasets. Click the + buttons to view associations for PTK2 from the datasets below. If available. Focal adhesion tyrosine kinase (PTK2) is often overexpressed in human hepatocellular carcinoma (HCC), and several reports have linked PTK2 depletion and/or pharmacol. inhibition to reduced tumorigenicity. However, the clin. relevance of targeting PTK2 still remains to be proven. Here, we present two highly selective and functional PTK2 proteolysis-targeting chimeras utilizing von Hippel-Lindau.

PTK2 protein expression summary - The Human Protein Atla

Anti-Focal adhesion kinase 1 (PTK2) (Hu) aus Kaninchen - unkonj. - Dianova. Zur Navigation springen Zum Inhalt springen. Suche nach: Suche. 0,00 € 0 Artikel; eMail: info@dianova.de. Tel.: +49 (0)40 / 450670. EN. Menü. Eigene Produkte. anti-IDH1 R132H; anti-ATRX; Anti-TIGIT; Anti-CD73; Anti-CD8; Anti-CD112R/PVRIG; Anti-FOXP3; Anti-CALR mut; Anti-His Epitop-Tag; His-Tag WB Staining Solution. 5 players compete in the Dec 13, 2020 Great Arena. 5+1 rated games are played during 30 minutes. Savagekitty takes the prize home PTK2 / YJR059W Interactions Interaction annotations are curated by BioGRID and include physical or genetic interactions observed between at least two genes. An interaction annotation is composed of the interaction type, name of the interactor, assay type (e.g., Two-Hybrid), annotation type (e.g., manual or high-throughput), and a reference. Experimental details, phenotype, modification, and.

proteins in the Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1) protein complex from the CORUM Protein Complexes dataset. ITGAV-ITGB3-PXN-PTK2b complex Gene Set. From CORUM Protein Complexes. proteins in the ITGAV-ITGB3-PXN-PTK2b complex protein complex from the CORUM Protein Complexes dataset. ArgBP2a-CBL-PTK2B complex Gene Set. Jetzt Anti-PTK2, Artikelnummer: G-CAB0024.100 von Antibody Genie bei Biomol kaufen Reactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge PTK2 (uc011ljr.2) at chr8:141668481-142011412 - Homo sapiens protein tyrosine kinase 2 (PTK2), transcript variant 3, mRNA. PTK2 (uc011ljq.2) at chr8:141668481-141810675 - Homo sapiens protein tyrosine kinase 2 (PTK2), transcript variant 3, mRNA ptk2 protein tyrosine kinase 2 View associated diseases Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis

PTK2 rabbit purified polyclonal antibody (20 μg) 2. PLCG1 mouse monoclonal antibody (40 μg) *Reagents are sufficient for at least 30-50 assays using recommended protocols. Application Details (hide) Application Notes Optimal working dilution should be determined by the investigator. Comment . Product Quality tested by: Protein protein interaction immunofluorescence result. Restrictions For. PTK2-001: OTTHUMT00000378054.5: 4955: 1052aa: OTTHUMP00000226318 <p>Genes and/or transcript that contains an open reading frame (ORF).</p> Protein coding. CCDS6381: Q05397: PTK2-011: OTTHUMT00000378103.1: 4414: 1065aa: OTTHUMP00000226350 <p>Genes and/or transcript that contains an open reading frame (ORF).</p> Protein coding. CCDS56557 -PTK2-057: OTTHUMT00000378540.1: 4405: 1052aa. The aim of the study was to investigate two single nucleotide polymorphisms (SNP) in PTK2 for associations with human muscle strength phenotypes in healthy men. Measurement of maximal isometric voluntary knee extension (MVCKE) torque, net MVCKE torque and vastus lateralis (VL) specific force, using established techniques, was completed on 120 Caucasian men (age = 20.6 ± 2.3 year; height = 1. No community annotations yet for PTK2. Sort mutations by: Tumor type Mutation type Position Straightedge cursor Expand. Figure notes • Mouse over a mutation to see details. • Missense green saturation indicates evolutionary conservation of the mutated positions. • Red hashes in protein strip are splice sites. • Blue-white-red bars are log2 copy ratio distributions (-1 to +1) from.

Molecular Expressions Cell Biology: Mitosis with

PTK2_ENST00000522684 - Explore an overview of PTK2_ENST00000522684, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data Buy Anti-PTK2, item number: G-CAB2114.100 from Antibody Genie at Biomol

5747 - Gene ResultPTK2 protein tyrosine kinase 2 [ (human)

Translation — ptk2 — from english — — 1. PtK2(NBL-5)细胞系(CCL56) Medical Chinese dictionary (湘雅医学词典) > PtK2(NBL-5)cells(CCL56) 3 PtK2(NBL-5)细胞 Focal adhesion tyrosine kinase (PTK2) is often overexpressed in human hepatocellular carcinoma (HCC), and several reports have linked PTK2 depletion and/or pharmacological inhibition to reduced tumorigenicity. However, the clinical relevance of targeting PTK2 still remains to be proven. Here, we present two highly selective and functional PTK2 proteolysis-targeting chimeras utilizing von.

PtK2 - What does PtK2 stand for? The Free Dictionar

proteins in the Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1) protein complex from the CORUM Protein Complexes dataset. ITGAV-ITGB3-PXN-PTK2b complex Gene Set. From CORUM Protein Complexes. proteins in the ITGAV-ITGB3-PXN-PTK2b complex protein complex from the CORUM Protein Complexes dataset. ArgBP2a-CBL-PTK2B complex Gene Set. From CORUM. Ptk2 (marsupial - potoroo, kidney) SPECIES: marsupial - potoroo TISSUE/ORGAN: kidney ECACC catalog code: 88031601 Morphology: Epithelial-like Description: Potoroo kidney Viruses: See Properties Depositor: Obtained from ATCC, USA No restrictions. Patent: None Specified By Depositor Properties: Applications: Chromosome and replication studies . Available in the following LABORATORY: Part of the. 1 PTK2 This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an. Auf dem HUAWEI P40 Pro Google Dienste installieren? Ja, das geht (aktuell) wieder. In unserer ausführlichen Anleitung zeigen wir euch wie es funktioniert

Recombinant Hu&mouse Ptk2 Protein, Natural Form, Lab Use, Multiscales PTK2 PTK2 protein tyrosine kinase 2. Also known as: Ptk2, FADK, FAK, FAK1, FRNK, Fadk, pp125FAK Nomenclature accurate as of April 27, 2007. Gene Details: HGNC (human) MGI (mouse) RGD (rat) Entrez Gene Pages: Human Mouse Rat Cow. Orthology Predictions. Through MGI (human and other mammalian species) Through HGNC/HCOP (vertebrate and invertebrate orthologs) Existing GO Annotation. Use the links. PTK2 ELISA Kits The ELISA (enzyme-linked immunosorbent assay) is a widely used application for detecting and quantifying proteins and antigens from various samples. Target-specific ELISA kits are available from a variety of manufacturers and can help streamline your immunodetection experiments PTK2 protein tyrosine kinase 2 (PTK2), also known as Focal Adhesion Kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. PTK2 is a focal adhesion-associated protein kinase involved in cellular adhesion (how cells stick to each other and their surroundings) and spreading processes (how cells move around). It has been shown that when FAK was blocked, breast cancer cells. Recombinant PTK2 Protein tyrosine Kinase 2 (PTK2) Protein (GST tag). Species: Human. Source: Insect Cells. Order product ABIN5569839

Rat Kangaroo Cell Intermediate Filaments with FluoresceinZEISS Xradia Synchrotron X-ray Imaging

Ptk2 cells - Wikipedi

The role of PTK2 as a major player in suppressing the apoptosis of cancer cell has been well revealed, and PTK2 is often expressed at aberrant high levels in cancer cells [22-24]. Studies have identified its downstream target PI3K-AKT pathway was involved in the functions of various kinds of cells including apoptosis [ 13 , 25 , 26 ] The PtK2 epithelial cell culture illustrated in this section was transfected with a chimeric EGFP plasmid vector that expresses a fluorescent fusion protein targeted at keratin intermediate filament networks. The specimen was also stained for mitochondria with MitoTracker Red CMXRos, and for the nucleus with the DNA-selective compound Hoechst 33342 (pseudocolored cyan) SC - https://soundcloud.com/icedoutptkFB PAGE - www.facebook.com/PTK-161435653905138/?ref=hlIG - www.instagram.com/takahiroryuu/S/O - CannabisshopFB - www.fa.. Ab1-ptk2 from the ZFIN a= ntibody database. =20 =20 =20 Other names, clone ids, catalog ids etc. =20 44-624G , anti-pY397 FAK , Biosource 44-624 = , ptk2 =20 =20 =20 Antibody Registry ID. =20 AB_1500097 =20 =20 =20 Does it work on zebrafish? =20 yes =20 =20 =20 Host organism =20 Rabbit =20 =20 =20 Immunogen organism =20 Human =2 PTK2 protein tyrosine kinase 2 (PTK2), also known as focal adhesion kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene.wikipedia. 116 Related Articles [filter] Tyrosine kinase. 100% (1/1) tyrosine kinases protein-tyrosine kinase protein tyrosine kinase. This gene encodes a cytosolic protein tyrosine kinase that is found concentrated in the focal adhesions that form among.

PathCards :: S-1P Stimulated Signaling Pathway and relatedRat Kangaroo Cytokeratin Intermediate Filaments with Alexa

PTK2 polyclonal antibody Catalog Number: PAB18503 Regulation Status: For research use only (RUO) Product Description: Rabbit polyclonal antibody raised against synthetic peptide of PTK2. Immunogen: A synthetic peptide corresponding to human PTK2. Host: Rabbit Reactivity: Human,Mouse,Rat Applications: ELISA, IHC-P, WB-Ce (See our web site product page for detailed application PtK2 cells are susceptible to coxsackievirus A9, herpes simplex, vaccinia, and vesicular stomatitis (Ogden strain). The cells are resistant, however, to adenovirus 5, coxsackievirus B5, and poliovirus 2. The PtK2 epithelial cell line is utilized for a variety of applications, but primarily for research in the field of mitosis. Mitosis is a phenomenon observed in all higher eukaryotes that. Mutations of Q05397 | PTK2 | Focal adhesion kinase 1 - Also known as FAK1_HUMAN, PTK2, FAK, FAK1. Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, | canSAR. can SAR Black Menu About us.

PTK2B Gene - GeneCards FAK2 Protein FAK2 Antibod

PTK2 gene expression in Bgee. Bgee allows to automatically compare gene expression patterns between species, by referencing expression data on anatomical ontologies, and designing homology relationships between them This article is about the protein. For the cell line, see Ptk2 cells. PTK2 Available structures PDB Ortholog search: PDBe RCSB. DGIdb, The Drug Gene Interaction Database, is a research resource that can be used to search candidate genes or drugs against the known and potentially druggable genome Immunogen: Mouse Ptk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-453 amino acids from the Central region of Mouse Ptk2. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States.

Ptk2 - Focal adhesion kinase 1 - Mus musculus (Mouse

Overvview of P34152 | Ptk2 | Focal adhesion kinase 1 - Also known as FAK1_MOUSE, Ptk2, Fadk, Fak, Fak1, Kiaa4203. Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhes... | canSAR . Overvview of P34152 | Ptk2 | Focal adhesion kinase 1 - Also known as FAK1_MOUSE, Ptk2, Fadk, Fak, Fak1, Kiaa4203. Non-receptor protein-tyrosine kinase that plays an. PTK2 HEK293T cell transient overexpression lysate (as WB positive control The human gene PTK2, encoding FAK, is localized at chromosome 8q24.3, a region characterized by frequent aberrations in human cancers. Focal adhesion kinase (FAK) is a multifunctional regulator of cell signal transduction in the tumor microenvironment. FAK promotes cell migration, survival, and proliferation through kinase-dependent and -independent mechanisms in various tumors. Elevated.

Rat Kangaroo Kidney Cell Actin | MicroscopyURole of Host Type IA Phosphoinositide 3-Kinase PathwayNovel red fluorophores with superior performance in STED

Focal Adhesion Kinase (FAK) Cite this entry as: (2018) PTK2. In: Choi S. (eds) Encyclopedia of Signaling Molecules PTK2 polyclonal antibody Catalog Number: PAB16301 Regulation Status: For research use only (RUO) Product Description: Rabbit polyclonal antibody raised against synthetic peptide of PTK2. Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human PTK2. Host: Rabbit Reactivity: Bovine,Chicken,Dog,Gorilla,Hamster,Human,Monkey,M ouse,Rat Applications: IHC-P (See our web site. PTK2 protein tyrosine kinase 2 (PTK2), also known as focal adhesion kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene.PTK2 is a focal adhesion-associated protein kinase involved in cellular adhesion (how cells stick to each other and their surroundings) and spreading processes (how cells move around). It has been shown that when FAK was blocked, breast cancer cells became.

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